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Intra uterine insemination.

Intra uterine insemination is one of the first line of management for treating infertility which involves directly inserting specially washed semen sample into the patient’s womb aroundthe time of ovulation.Hormonal supplements may be used in conjunction with the treatment to enhance the chances of conception. Benefit: A relatively small number of sperms reach the site of fertilization i.e. fallopian tubes during intercourse.IUI inserts good amount of motile sperms directly into woman’s uterus thus increasing the rate of fertilization. Which couples benefit from IUI?

  • Abnormal semen profile
  • Ovulatory dysfunction
  • Cervical factor
  • Unilateral tubal block
  • Immunological factor
  • Unexplained infertility
  • Ejaculation problems
  • Mild endometriosis
Conditions in which IUI is not suitable
  • Blocked or damaged fallopian tubes
  • Poor ovarian reserve
  • Severe male factor infertility
  • Severe endometriosis
Step by Step in IUI
  • Basic blood investigations and semen analysis
  • Baseline sonography on Day 2 of periods followed by starting medication for development and maturation of 2-3 eggs
  • Monitoring the growth of follicles by vaginal sonography every 2-3 days and individualize drug doses
  • Hormonal injection is given for rupture of follicles once they attain adequate size
  • Semen sample provided on the day of ovulation, is washed,prepared and deposited into womb on that day
  • Medications to support the pregnancy are given and pregnancy test is done after 2 weeks of IUI

Basic Principles of IUI
  1. Selection of most functional sperms from ejaculate.
  2. Removal of cellular debris and Seminal Plasma.
  3. Adding of substance which causes increase in sperm motility.
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